At GBT, we collaborate with academic centers to present and publish key results at medical conferences and in peer-reviewed publications. For additional information related to our data presentations and publications, please contact 1-833-GBT-4YOU (1-833-428-4968) or visit the GBT Online Form.

Selected Key Transcranial Doppler Research

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia—TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial
The Lancet, Ware et al, December 2015

Controlled Trial of Transfusions for Silent Cerebral Infarcts in Sickle Cell Anemia
The New England Journal of Medicine, DeBaun et al, August 2014

Stroke With Transfusions Changing to Hydroxyurea (SWiTCH)
Blood, Ware and Helms, April 2012

Effect of Transfusion Therapy on Transcranial Doppler Ultrasonography Velocities in Children With Sickle Cell Disease
Pediatric Blood & Cancer, Kwiatkowski et al, December 2010

Discontinuing Prophylactic Transfusions Used to Prevent Stroke in Sickle Cell Disease
The New England Journal of Medicine, Adams et al, December 2005

Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
The New England Journal of Medicine, Adams et al, July 1998

Cerebrovascular Accidents in Sickle Cell Disease: Rates and Risk Factors
Blood, Ohene-Frempong et al, January 1998